细胞生物学考研，细胞生物学考研学校排名
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1. 本人的研究方向为“病原菌致病与耐药机制的研究”，主要致力于以下两个方面：
围绕“类脂A的结构修饰”这一科学问题，从脂代谢角度解析“MCR基因家族多粘菌素耐药的遗传进化、蛋白结构基础和流行传播”的分子机制。不仅探明了类脂A是细菌对多粘菌素抗生素药物的耐药代谢基础，而且提出了MCR基因家族介导多粘菌素耐药的酶学催化机理和遗传进化机制模型。相关成果发表在Cell Reports、mBio、Ebiomedicine等国际知名杂志。
围绕“生物素代谢”这一科学问题，阐明了生物素BioZ合成通路的结构与生化机制，发现合成生物素的新途径；挖掘分枝杆菌BioC-BioH生物素合成途径的关键基因，解析生物素代谢与病原菌致病的关系，为新抗菌靶标的挖掘/小分子药物设计提供理论支持。相关成果发表在Science Advancesd、 Nature Communications、PLoS Pathogens等杂志。
2. 招生要求：具有英文文献阅读能力，踏实勤奋，刻苦上进
3. 学生培养：提供高于学校规定的学生津贴，支持申报研究生国家奖助学金，提供机会与浙江大学、南开大学等国内双一流高校交流合作，鼓励支持攻读博士学位
4. 导师发表论文：
1. Xu Y# , Yang J# , Li W# , Song S# , Shi Y# , Wu L, Sun J, Hou M, Wang J, Jia X, Zhang H, Huang M, Lu T, Gan J*, Feng Y*. Three enigmatic BioH isoenzymes are programmed in the primary step of mycobacterial biotin synthesis, an attractive anti-TB drug target. PLoS Pathogens 2022. SCI Top,一区 (IF 7.913 )
2. Xu Y# , Chen H# , Zhang H# , Ullah S# , Hou T*, Feng Y*. The MCR-3 inside linker appears as a facilitator of colistin resistance. Cell Reports 2021. SCI Top,一区 (IF 10.990)
3. Zhang S# , Xu Y# , Guan H# , Cui T#, Liao Y#, Wei W#, Li J, Hassan BH, Zhang H, Jia X, Ouyang S*, Feng Y*. Biochemical and structural characterization of the BioZ enzyme engaged in bacterial biotin synthesis pathway. Nature Communications 2021.SCI Top, 一区 (IF 17.763)
4. Xu Y, Liu L, Zhang H, Feng Y*. Co-production of Tet(X) and MCR-1, two resistance enzymes by a single plasmid. Environmental Microbiology 2021. SCI , 一区 (IF 6.820)
5. Xu Y, Liu L, Sun J, Feng Y*. Limited distribution and mechanism of the TetX4 tetracycline resistance enzyme. Science Bulletin 2019. SCI Top, 一区 (IF 20.577)
6. Xu Y# , Zhong LL# , Srinivas S# , Sun J# , Huang M, Paterson DL, Lei S, Lin J, Li X, Tang Z, Feng S, Shen C, Tian GB*, Feng Y*. Spread of MCR-3 colistin resistance in China: An epidemiological, genomic and mechanistic study. EBioMedicine 2018. SCI Top, 一区 (IF 11.205)
7. Xu Y# , Wei W# , Lei S# , Lin J# , Srinivas S, Feng Y*. An evolutionarily conserved mechanism for intrinsic and transferable polymyxin resistance. mBio 2018. SCI Top,一区 (IF 8.483)
8. Xu Y# , Lin J# , Cui T# , Srinivas S, Feng Y*. Mechanistic insights into transferable polymyxin resistance among gut bacteria. J Biol Chem 2018. SCI ,二区 (IF 5.041)
9. Xu Y, Wang L, Jia X, Feng Y*. 2019 nCoV: A possible progenitor for SARS-CoV with Bat origin? Preprints 2020.
10. Ji K# , Xu Y# , Sun J, Huang M, Jia X, Jiang C*, Feng Y*. Harnessing efficient multiplex PCR methods to detect the expanding Tet(X) family of tigecycline resistance genes. Virulence 2020.SCI ,一区 (IF 6.735)
11. Sun J# , Xu Y# , Gao R# , Lin J# , Wei W, Srinivas S, Li D, Yang RS, Li XP, Liao XP, Liu YH*, Feng Y*. Deciphering MCR-2 Colistin Resistance. mBio 2017.SCI Top,一区 (IF 8.483)
12. Zhang H# , Hou M# , Xu Y# , Srinivas S, Huang M, Liu L, Feng Y*. Action and mechanism of the colistin resistance enzyme MCR-4. Communications Biology 2019. SCI,一区 (IF 6.816)
13. Umar Z#, Chen Q#, Tang B#, Xu Y#, Wang J, Zhang H, Ji K, Jia X, Feng Y*. The poultry pathogen Riemerella anatipestifer appears as a reservoir for Tet(X) tigecycline resistance. Environmental Microbiology 2021.SCI Top,一区 (IF 6.820)
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细胞生物学考研(细胞生物学考研学校排名)